Clinical Evidence

Research & Science

Every treatment we offer is grounded in peer-reviewed science. Browse the clinical trials and mechanism studies that inform our approach.

Methods tracked

Papers indexed

Structured analyses

lifestyle

General Hair Loss

Grade C

42 linked papers with evidence grade C.

Papers

Participants

156

Headline

23 % avg effect

pharmacological

Minoxidil

Grade B

29 linked papers with evidence grade B. Best indexed study enrolled 466 participants.

Papers

Participants

2,227

Headline

20.2 hairs/cm2 avg effect

pharmacological

Finasteride

Grade B

20 linked papers with evidence grade B. Best indexed study enrolled 458 participants.

Papers

Participants

458

Headline

12.4 hairs/cm2 avg effect

device

PRP

Grade C

13 linked papers with evidence grade C.

Papers

Participants

1,127

Headline

Structured extraction limited

device

Low-Level Laser Therapy

Grade C

11 linked papers with evidence grade C.

Papers

Participants

N/A

Headline

Structured extraction limited

supplement

Saw Palmetto

Grade B

10 linked papers with evidence grade B. Best indexed study enrolled 80 participants.

Papers

Participants

140

Headline

29 % reduction in hair fall avg effect

surgical

Hair Transplant

Grade C

9 linked papers with evidence grade C.

Papers

Participants

112

Headline

55.35 % avg effect

device

Microneedling

Grade B

9 linked papers with evidence grade B. Best indexed study enrolled 466 participants.

Papers

Participants

1,593

Headline

12.29 β avg effect

pharmacological

Dutasteride

Grade C

8 linked papers with evidence grade C.

Papers

Participants

N/A

Headline

Structured extraction limited

supplement

Biotin

Grade B

6 linked papers with evidence grade B. Best indexed study enrolled 50 participants.

Papers

Participants

206

Headline

23 % avg effect

pharmacological

Ketoconazole

Grade C

3 linked papers with evidence grade C.

Papers

Participants

N/A

Headline

7 interventions best indexed study

device

Stem Cell Therapy

Grade C

3 linked papers with evidence grade C.

Papers

Participants

N/A

Headline

Structured extraction limited

device

Exosome Therapy

Grade C

2 linked papers with evidence grade C.

Papers

Participants

N/A

Headline

Structured extraction limited

pharmacological

Spironolactone

Grade C

2 linked papers with evidence grade C.

Papers

Participants

N/A

Headline

Structured extraction limited

pharmacological

DHT Pathway

Grade C

1 linked papers with evidence grade C.

Papers

Participants

N/A

Headline

promising qualitative assessment best indexed study

SearchMethodStudy typeSort

Saw PalmettoSaw Palmetto

Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.

Ahmed A, Alali AM, Abdullah E, Alharbi MN, Alayoubi HM · Skin appendage disorders · 2026

Herbal remedies such as saw palmetto, rosemary, and others show promise for promoting hair growth in various types of hair loss via mechanisms like 5α-reductase inhibition and increased microcirculation, though evidence is limited.

Study

review

Population

N/A

Key result

Pending extraction

Citations

N/A

Confidence

low

Tags

condition:androgenetic_alopecia, condition:telogen_effluvium, condition:alopecia_areata

Saw PalmettoSaw Palmetto

The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.

Ablon G · Journal of cosmetic dermatology · 2025

Daily oral administration of a proprietary saw palmetto extract significantly increased terminal hair count (7-fold) and total hair count (12-fold) compared to placebo while reducing hair shedding.

Study

rct

Population

60 participants

Key result

7-fold improvement compared to placebo fold

Citations

N/A

Confidence

high

Tags

condition:androgenetic_alopecia, sex:male, sex:female

FinasterideDutasterideFinasteride

A Canadian Consensus on Androgenetic Alopecia: Approach and Management.

Landells I, Chow E, Gupta AK, Jasso Olivares JC, Thuraisingam T, Ahluwalia R, Tan JKL, Pratt M, Yadav G, Chivers Q, Vezina N, Laforest T, Raad E, Owen J, Dayeh NR · Journal of cutaneous medicine and surgery · 2025

A consensus of experts identified seven recommended interventions for AGA, including oral and topical finasteride, dutasteride, and minoxidil, while identifying 17 interventions that are not recommended.

Study

review

Population

N/A

Key result

7 interventions

Citations

N/A

Confidence

moderate

Tags

condition:androgenetic_alopecia, sex:male, sex:female

Saw PalmettoSaw PalmettoGeneral Hair Loss

Topical Alternatives for Hair Loss: Beyond the Conventional.

Bikash C · International journal of trichology · 2025

Topical actives like Redensyl and Procapil show promising results, often in combined formulations, but clinical evidence is limited by small sample sizes and lack of standardized comparisons.

Study

review

Population

N/A

Key result

Pending extraction

Citations

N/A

Confidence

low

Tags

route:topical, outcome:hair_regrowth, safety:well_tolerated

Laser TherapyLow-Level Laser TherapyGeneral Hair Loss

Gray Hair: From Preventive to Treatment.

Herdiana Y · Clinical, cosmetic and investigational dermatology · 2025

The review identifies topical melanin stimulants, antioxidants, dietary supplements, and LLLT as promising approaches for managing gray hair.

Study

review

Population

N/A

Key result

Pending extraction

Citations

N/A

Confidence

low

Tags

condition:androgenetic_alopecia, population:adult, outcome:patient_satisfaction

MinoxidilMinoxidilSaw Palmetto

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.

Leavitt A, Hawkins SD, Kindred C, Frey C, Gainers M, Grekin SK, Leavitt M · Journal of drugs in dermatology : JDD · 2025

The review highlights that while FDA-approved treatments are limited, natural supplements like saw palmetto and pumpkin seed oil show promise in inhibiting 5-alpha-reductase and promoting hair density.

Study

review

Population

N/A

Key result

inhibits 5-alpha-reductase n/a

Citations

N/A

Confidence

moderate

Tags

condition:androgenetic_alopecia, condition:female_pattern_hair_loss, condition:alopecia_areata

FinasterideDutasterideMinoxidil

Topical dutasteride for androgenic alopecia: current state and prospects.

Andrade JFM, Verbinnen A, Bakst A, Cunha-Filho M, Gelfuso GM, Gratieri T · Therapeutic delivery · 2025

The review discusses the potential of topical dutasteride and nanocarrier delivery systems to provide an effective alternative to oral treatments while minimizing systemic absorption.

Study

review

Population

N/A

Key result

Pending extraction

Citations

N/A

Confidence

high

Tags

condition:androgenetic_alopecia, condition:female_pattern_hair_loss, condition:male_pattern_hair_loss

FinasterideFinasterideDutasteride

Comparison between dutasteride and finasteride in hair regrowth and reversal of miniaturization in male and female androgenetic alopecia: a systematic review.

Almudimeegh A, AlMutairi H, AlTassan F, AlQuraishi Y, Nagshabandi KN · Dermatology reports · 2025

Dutasteride (0.5 mg and 2.5 mg) is significantly more effective than finasteride (1 mg) at increasing hair counts in both males and females with AGA.

Study

review

Population

N/A

Key result

significant increase participants

Citations

N/A

Confidence

moderate

Tags

condition:androgenetic_alopecia, condition:female_pattern_hair_loss, condition:male_pattern_hair_loss

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