pharmacological

Spironolactone

7 linked papers with evidence grade B. Best indexed study enrolled 5290 participants.

Product links

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Evidence Grade

B

Linked Papers

7

Participants

5,320

Average Efficacy

26.5 %

Summary

7 linked papers with evidence grade B. Best indexed study enrolled 5290 participants.

Best indexed study: Interventions for female pattern hair loss. (2016)

Side Effects

post-finasteride syndrome1 study
Minoxidil 2% adverse event rate 9.8% vs placebo 8.8% (RR 1.24)1 study
No significant difference in adverse events between minoxidil 2% and 5% (RR 1.02)1 study
Finasteride adverse event rate not significantly different from placebo (RR 1.03)1 study
potential complications with medications1 study
lack of profound benefit with laser and light therapies1 study

Linked studies

Papers behind Spironolactone

Confidence

low

Combining PRP with pharmacological support during FUE hair transplantation significantly improves follicle survival, growth rates, and hair strength compared to pharmacological support alone.

Extracted key result

significantly improved follicle growth rates

30 participants

Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs.

Clinical, cosmetic and investigational dermatology · 2023 · Kaiser M, Abdin R, Gaumond SI, Issa NT, Jimenez JJ

Confidence

low

Standard treatments like topical minoxidil and oral finasteride are established, while newer modalities like PRP, LLLT, and oral minoxidil show encouraging results but lack standardized protocols.

Extracted key result

Pending structured analysis

Sample size not extracted

Lasers, lights, and compounds for hair loss in aesthetics.

Clinics in dermatology · 2022 · Ring CM, Finney R, Avram M

Confidence

moderate

The review discusses various promising topical, oral, and energy-based therapies, noting growing evidence for their efficacy in treating hair loss.

Extracted key result

Pending structured analysis

Sample size not extracted

Female Androgenetic Alopecia: An Update on Diagnosis and Management.

American journal of clinical dermatology · 2020 · Starace M, Orlando G, Alessandrini A, Piraccini BM

Confidence

moderate

Topical minoxidil and oral anti-androgens are the primary treatments aimed at halting progression and promoting cosmetically acceptable hair regrowth in female pattern hair loss.

Extracted key result

33.3 %

Sample size not extracted

Interventions for female pattern hair loss.

The Cochrane database of systematic reviews · 2016 · van Zuuren EJ, Fedorowicz Z, Schoones J

Confidence

moderate

Topical minoxidil shows moderate efficacy in increasing hair regrowth and hair count in women with FPHL, with no clear advantage of 5% over 2% concentration; oral finasteride 1 mg is not more effective than placebo; low-level laser therapy may increase hair count but clinical relevance is uncertain.

Extracted key result

13.18 hairs/cm²

5290 participants

Female pattern alopecia: current perspectives.

International journal of women's health · 2014 · Levy LL, Emer JJ

Confidence

moderate

Current treatments (minoxidil, finasteride) offer limited and non-permanent benefits; hair transplantation is the only permanent option, while other off-label agents and laser therapies are commonly used despite modest or inconsistent efficacy.

Extracted key result

Pending structured analysis

Sample size not extracted

Androgenetic alopecia.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia · 2014 · Piraccini BM, Alessandrini A

Confidence

moderate

Treatments such as topical minoxidil and 5‑alpha reductase inhibitors (finasteride, dutasteride) can slow hair loss progression and promote regrowth, but continuous use is required to maintain benefit.

Extracted key result

Pending structured analysis

Sample size not extracted