supplement
7 linked papers with evidence grade B. Best indexed study enrolled 50 participants.
Evidence Grade
B
Linked Papers
7
Participants
224
Average Efficacy
23 %
Summary
7 linked papers with evidence grade B. Best indexed study enrolled 50 participants.
Best indexed study: Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands. (2022)
Side Effects
Linked studies
Clinical, cosmetic and investigational dermatology · 2025 · Herdiana Y
Confidence
low
The review identifies topical melanin stimulants, antioxidants, dietary supplements, and LLLT as promising approaches for managing gray hair.
Extracted key result
Pending structured analysis
Sample size not extracted
Anais brasileiros de dermatologia · 2024 · Valentim FO, Miola AC, Miot HA, Schmitt JV
Confidence
low
The study investigates the comparative efficacy of topical minoxidil, oral biotin, and their combination on hair growth in men, but specific numeric results are not provided in the abstract.
Extracted key result
Pending structured analysis
Sample size not extracted
The Journal of clinical and aesthetic dermatology · 2024 · Yelich A, Jenkins H, Holt S, Miller R
Confidence
high
High-quality evidence does not support the use of biotin as a hair supplement for hair growth or quality.
Extracted key result
no difference participants
Sample size not extracted
Clinics in dermatology · 2022 · Ring CM, Finney R, Avram M
Confidence
moderate
The review discusses various promising topical, oral, and energy-based therapies, noting growing evidence for their efficacy in treating hair loss.
Extracted key result
Pending structured analysis
Sample size not extracted
Dermatologic therapy · 2022 · Samadi A, Ketabi Y, Firooz R, Firooz A
Confidence
high
Intramuscular biotin and dexpanthenol injections significantly improved hair fall count and total hair density in patients with diffuse hair loss, with the Bayer brand showing superior terminal/vellus hair ratio improvement.
Extracted key result
significantly improved p-value <0.01
50 participants
Journal of laparoendoscopic & advanced surgical techniques. Part A · 2021 · Şen O, Türkçapar AG
Confidence
moderate
Hair loss is common after sleeve gastrectomy, typically occurring between months 3 and 4. Biotin supplementation shows low efficacy in reducing hair loss regardless of biotin deficiency status.
Extracted key result
23 %
156 participants
Skin appendage disorders · 2020 · Patel DP, Swink SM, Castelo-Soccio L
Confidence
low
Biotin supplementation showed clinical improvement in individuals with underlying biotin deficiency or hair/nail pathologies, but evidence for efficacy in healthy individuals is lacking.
Extracted key result
Pending structured analysis
18 participants