supplement

Saw Palmetto

11 linked papers with evidence grade B. Best indexed study enrolled 80 participants.

Evidence Grade

B

Linked Papers

11

Participants

140

Average Efficacy

29 % reduction in hair fall

Summary

11 linked papers with evidence grade B. Best indexed study enrolled 80 participants.

Best indexed study: Oral and Topical Administration of a Standardized Saw Palmetto Oil Reduces Hair Fall and Improves the Hair Growth in Androgenetic Alopecia Subjects - A 16-Week Randomized, Placebo-Controlled Study. (2023)

Side Effects

no adverse events were reported1 study
less significant side effect profile1 study
Biotin supplementation may cause diagnostic test interference1 study
minimal side effects1 study
No serious adverse effects were observed1 study
oral finasteride may cause undesirable side effects1 study

Linked studies

Papers behind Saw Palmetto

Herbal Remedies for Hair Loss: A Review of Efficacy and Safety.

Skin appendage disorders · 2026 · Ahmed A, Alali AM, Abdullah E, Alharbi MN, Alayoubi HM

Confidence

low

Herbal remedies such as saw palmetto, rosemary, and others show promise for promoting hair growth in various types of hair loss via mechanisms like 5α-reductase inhibition and increased microcirculation, though evidence is limited.

Extracted key result

Pending structured analysis

Sample size not extracted

Daily oral administration of a proprietary saw palmetto extract significantly increased terminal hair count (7-fold) and total hair count (12-fold) compared to placebo while reducing hair shedding.

Extracted key result

7-fold improvement compared to placebo fold

60 participants

Topical Alternatives for Hair Loss: Beyond the Conventional.

International journal of trichology · 2025 · Bikash C

Confidence

low

Topical actives like Redensyl and Procapil show promising results, often in combined formulations, but clinical evidence is limited by small sample sizes and lack of standardized comparisons.

Extracted key result

Pending structured analysis

Sample size not extracted

Addressing the Root Causes of Female Hair Loss and Non-Pharmaceutical Interventions.

Journal of drugs in dermatology : JDD · 2025 · Leavitt A, Hawkins SD, Kindred C, Frey C, Gainers M, Grekin SK, Leavitt M

Confidence

moderate

The review highlights that while FDA-approved treatments are limited, natural supplements like saw palmetto and pumpkin seed oil show promise in inhibiting 5-alpha-reductase and promoting hair density.

Extracted key result

inhibits 5-alpha-reductase n/a

Sample size not extracted

Oral and Topical Administration of a Standardized Saw Palmetto Oil Reduces Hair Fall and Improves the Hair Growth in Androgenetic Alopecia Subjects - A 16-Week Randomized, Placebo-Controlled Study.

Clinical, cosmetic and investigational dermatology · 2023 · Sudeep HV, Rashmi S, Jestin TV, Richards A, Gouthamchandra K, Shyamprasad K

Confidence

high

Both oral and topical saw palmetto oil significantly reduced hair fall and increased hair density in subjects with AGA, with oral administration also reducing serum DHT levels.

Extracted key result

29 % reduction in hair fall

80 participants

Natural Compounds Used for Treating Hair Loss.

Current pharmaceutical design · 2023 · Gasmi A, Mujawdiya PK, Beley N, Shanaida M, Lysiuk R, Lenchyk L, Noor S, Muhammad A, Strus O, Piscopo S, Komisarenko A, Fedorovska M, Bjørklund G

Confidence

low

Medicinal plants and natural compounds show potential in promoting hair growth and preventing alopecia through anti-inflammatory, antioxidant, and metabolic improvement properties.

Extracted key result

Pending structured analysis

Sample size not extracted

Natural products for male androgenetic alopecia.

Dermatologic therapy · 2022 · Gupta AK, Talukder M, Bamimore MA

Confidence

moderate

Natural products such as saw palmetto, caffeine, and rosemary oil may serve as alternatives or adjuncts to conventional minoxidil and finasteride treatments for male AGA.

Extracted key result

Pending structured analysis

Sample size not extracted

An overview of herbal alternatives in androgenetic alopecia.

Journal of cosmetic dermatology · 2019 · Dhariwala MY, Ravikumar P

Confidence

low

Herbal drugs may reduce hair loss by inhibiting the 5-alpha-reductase enzyme with potentially fewer side effects than conventional pharmacological treatments.

Extracted key result

53 minutes

Sample size not extracted